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Search Results for " Human immunodeficiency virus "

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197

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天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
TP1809	TAT		HIV Protease
	TAT peptide (YGRKKRRQRRR), originating from the human immunodeficiency virus-1 (HIV-1) transactivator of transcription (TAT), enhances the solubility and production of heterologous proteins[1]. This cell-penetrating pept...		HIV Protease
T38514	PMEDAP		Others , HIV Protease
	PMEDAP is a potent inhibitor of Moloney murine sarcoma virus (MSV)-induced tumor formation and associated mortality and an inhibitor of human immunodeficiency virus (HIV) replication. PMEDAP also has anti-murine cytomega...		Others , HIV Protease
T12953	Sodium copper chlorophyllin B		Influenza Virus , HIV Protease
	Sodium copper chlorophyllin B exerts antiviral activities against Influenza virus and HIV.		Influenza Virus , HIV Protease
T10111	3-Deazaadenosine hydrochloride		Others , HIV Protease
	3-Deazaadenosine hydrochloride is an inhibitor of S-adenosylhomocysteine hydrolase (Ki: 3.9 µM). It has anti-inflammatory, anti-proliferative, and anti-HIV activity.		Others , HIV Protease
T12715	Reverse transcriptase-IN-1		HIV Protease
			HIV Protease
T16764	RN-18		HIV Protease
	RN-18 is an inhibitor of HIV-1 viral infectivity factor (IC50: 6 μM in nonpermissive H9 cells).		HIV Protease
T15436	GSK2838232		HIV Protease
	GSK2838232 inhibit HIV reverse transcriptase activity across a broad panel of HIV-1 isolates,GSK2838232 is novel human immune virus (HIV) maturation inhibitor.		HIV Protease
T9063	Clathrin-IN-1		HIV Protease
	Clathrin-IN-1 is a inhibitor of clathrin, and inhibits clathrin-mediated endocytosis (CME) by associating with the terminal domain of clathrin. It has the potential for anti-cancer research.		HIV Protease
T16276	NBD-556		HIV Protease
	NBD-556 is a small molecule mimetic of CD4. NBD-556 recognizes the HIV-1 envelope protein gp120 and induces restructuring of gp120 analogous to CD4 binding.		HIV Protease
T6256	YYA-021	YYA 021	gp120/CD4 , HIV Protease
	YYA-021 inhibits HIV entry, with high anti-HIV activity and low cytotoxicity.		gp120/CD4 , HIV Protease
T4665	Temsavir	BMS626529	HIV Protease
	Temsavir (BMS626529) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells.		HIV Protease
T15210	Elsulfavirine	Elpida,VM-1500	HIV Protease
	Elsulfavirine (VM-1500) is an HIV-1 infection reverse transcriptase inhibitor. It is a new anti-HIV drug.		HIV Protease
T0836	Sulfadoxine	Sulphadoxine	DHFR , HIV Protease , Antibiotic , Parasite , Autophagy
	Sulfadoxine (Sulphadoxine) is a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with bacteriostatic and antimalarial properties.		DHFR , HIV Protease , Antibiotic , Parasite , Autophagy
T0457	Probenecid	Benemid	HIV Protease , Antibacterial , TRP/TRPV Channel
	Probenecid (Benemid) is a benzoic acid derivative with antihyperuricemic property.		HIV Protease , Antibacterial , TRP/TRPV Channel
T8311	Obefazimod	ABX-464,ABX464	HIV Protease
	Obefazimod (ABX-464) is a potent anti-HIV agent. ABX464 inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs) (IC50 : 0.1 μM - 0.5 μM)		HIV Protease
T3172	Trovirdine	LY300046	HIV Protease
	Trovirdine (LY300046) is a thiourea non-nucleoside reverse transcriptase inhibitor.		HIV Protease
T16098	Islatravir	MK-8591	HIV Protease , Reverse Transcriptase
	Islatravir (MK-8591) is an effective anti-HIV-1 agent. It acts as a nucleoside reverse transcriptase inhibitor (EC50s: 0.068 nM, 3.1 nM, and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively).		HIV Protease , Reverse Transcriptase
T9212	IMB-301		Others , HIV Protease
	IMB-301 is a small molecular inhibitor via virtual screening according to the hA3G model.		Others , HIV Protease
T13974	ZL0580		Epigenetic Reader Domain , HIV Protease
	ZL0580 induces HIV suppression by inhibiting Tat transactivation and transcription elongation as well as by inducing repressive chromatin structure at the HIV promoter.		Epigenetic Reader Domain , HIV Protease
T0289	9-Aminoacridine	Aminacrine	Others , HIV Protease , Antibacterial
	9-Aminoacridine is a highly fluorescent anti-infective dye used clinically as a topical antiseptic and experimentally as a mutagen, due to its interaction with DNA. It is also used as an intracellular pH indicator.		Others , HIV Protease , Antibacterial
T4493	Bictegravir	GS-9883	HIV Protease
	Bictegravir (GS-9883) is a potent inhibitor of HIV-1 integrase (IC50: 7.5 nM).		HIV Protease
T4557	Amylmetacresol	5-Methyl-2-Pentylphenol	Others , HIV Protease
	Amylmetacresol (5-Methyl-2-Pentylphenol) is used in the treatment of sore throat or 'acute sore throat', pharyngitis, tonsillitis and laryngitis. As well as in the treatment of influenza A and SARS-CoV.		Others , HIV Protease
T15371	Gardiquimod		TLR , HIV Protease
	Gardiquimod is a TLR7/8 agonist. When used at concentrations below 10 μM, Gardiquimod specifically activates TLR7. Gardiquimod could inhibit HIV-1 infection of macrophages and activated peripheral blood mononuclear cells...		TLR , HIV Protease
T10603	BRD-6929		HIV Protease , HDAC
	BRD-6929 is a selective, brain-penetrant HDAC1 and HDAC2 inhibitor (IC50: 1 and 8 nM). BRD-6929 (Cpd-60) shows high-affinity to HDAC1 and HDAC2 (Kis: 0.2 and 1.5 nM) [2]. BRD-6929 potentiates the efficacy of gnidimacrin...		HIV Protease , HDAC
T10133	3'-Azido-3'-deoxy-5-methylcytidine		Antiviral , HIV Protease
	3'-Azido-3'-deoxy-5-methylcytidine inhibits HIV-1 reverse transcriptase(EC50 = 0.06 μM) and is an effective inhibitor of xenotropic murine leukemia-related retrovirus (XMRV, CC50 = 43.5 μM).		Antiviral , HIV Protease
T11538	Hck-IN-1		HIV Protease , Src , Hck
	Hck-IN-1 is a selective Nef-dependent Hck inhibitor (IC50s: 2.8 μM and >20 μM for Nef:Hck complex and Hck) with antiretroviral activity. Hck-IN-1 is a direct and wide HIV-1 Nef antagonist with an IC50 of 100-300 nM for w...		HIV Protease , Src , Hck
T0781	Dimercaprol	Dicaptol,Dithiopropanol	Others , HIV Protease
	Dimercaprol (Dicaptol) is an anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the t...		Others , HIV Protease
T6846	Vesatolimod	GS-9620	Apoptosis , HCV Protease , HBV , TLR , HIV Protease
	Vesatolimod (GS-9620) is an effective and specific orally active agonist of Toll-like receptor 7.		Apoptosis , HCV Protease , HBV , TLR , HIV Protease
T10570	Fostemsavir Tris	BMS-663068 Tris	HIV Protease
	Fostemsavir Tris (BMS-663068 Tris) is the prodrug of BMS-626529,is a oral, safe and effective inhibitor of HIV-1 attachment. It inhibits human immunodeficiency virus type 1 (HIV-1) infection by binding to gp120 and inter...		HIV Protease
T9039	HIV-1 Nef-IN-1		HIV Protease
	HIV-1 Nef-IN-1 is an inhibitor of HIV-1 Nef protein. It efficiently competes for Nef-SH3Hck interactions(Kd : 6.7 μM).		HIV Protease
TQ0174	Mavorixafor	AMD-070	CXCR
			CXCR
T6007	Birinapant	TL32711	Apoptosis , IAP , HIV Protease
	Birinapant (TL32711) is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of IAP (Inhibitor of Apoptosis Protein) family proteins, with po...		Apoptosis , IAP , HIV Protease
T3523	Fostemsavir	BMS-663068	HIV Protease
	Fostemsavir (BMS-663068) is an HIV-1 attachment inhibitor in development for the treatment of HIV-1 infection.		HIV Protease
T8238	Fosamprenavir Calcium Salt	Diallyl Trisulfide,GW433908G	HIV Protease
	Fosamprenavir Calcium Salt (GW433908G) (GW433908G) is a phosphate ester prodrug of the antiretroviral protease inhibitor Amprenavir, with improved solubility. Fosamprenavir Calcium Salt has Anti-HIV infection.		HIV Protease
T0033	Miltefosine	HePC,Hexadecyl phosphocholine	Akt , HIV Protease , PKC
	Miltefosine (HePC) is the treatment of visceral and cutaneous leishmaniasis drug , and is proceeding clinical trials for this in several countries. Several medical agents produce some potency against visceral or cutaneou...		Akt , HIV Protease , PKC
T2239L	Raltegravir	MK-0518	HIV Protease , Integrase
	Raltegravir (MK-0518) is a pyrrolidinone derivative and HIV INTEGRASE INHIBITOR that is used in combination with other ANTI-HIV AGENTS for the treatment of HIV INFECTION.		HIV Protease , Integrase
T3614	Inosine pranobex	Groprinosin,Isoprinosine,Immunovir,Delimmun	IL Receptor , HIV Protease
	Inosine pranobex (Delimmun) has a number of immunomodulatory effects, including inducing T-lymphocyte differentiation, augmenting macrophage and NK cell functions, and stimulating IL-2 production. Through these effects a...		IL Receptor , HIV Protease
T11465	Lenacapavir	GS-6207	Others , HIV Protease
			Others , HIV Protease
T0753	Salicylanilide	WR10019,2-Hydroxybenzanilide	HIV Protease , Reverse Transcriptase
	Salicylanilide (2-Hydroxybenzanilide)s are a group of compounds with antiviral potency, antibacterial and antifungal activities.		HIV Protease , Reverse Transcriptase
TP1432	Enfuvirtide acetate		HIV Protease
	Enfuvirtide acetate salt is a linear synthetic peptide made of 36 amino acids. It has an acetylated N-terminus and a carboxamide C-terminus.		HIV Protease
T7903	Saquinavir	Ro 31-8959	SARS-CoV , HIV Protease
	Saquinavir (Ro 31-8959) is a potent HIV protease inhibitor, is an antiretroviral drug used together with other medications to treat or prevent HIV/AIDS.		SARS-CoV , HIV Protease
T0676	Hydroxyurea	Hydroxycarbamide,nsc32065,nci-c04831	Apoptosis , HIV Protease , DNA/RNA Synthesis , Autophagy
	Hydroxyurea (Hydroxycarbamide), an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.		Apoptosis , HIV Protease , DNA/RNA Synthesis , Autophagy
T5965	Ditiocarb sodium	Sodium diethyldithiocarbamate	HIV Protease
	Ditiocarb sodium (Sodium diethyldithiocarbamate) (sodium diethiocarbamate) is a copper reagent, which reacts with Cu2 + solution to form a complex and improves the precipitation rate of copper replacement. Sodium diethyl...		HIV Protease
T1883	Des(benzylpyridyl) Atazanavi		HIV Protease
	The N-dealkylated metabolite (M1) of Atazanavir, a HIV protease inhibitor.		HIV Protease
T4697	ABBV-744	ABBV744	Epigenetic Reader Domain , HIV Protease
	ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS.		Epigenetic Reader Domain , HIV Protease
T0282	Q-VD-OPH	Quinoline-Val-Asp-Difluorophenoxymethylketone	Caspase , HIV Protease
	Q-VD-OPH (Quinoline-Val-Asp-Difluorophenoxymethylketone) is a pan-caspase inhibitor with potent antiapoptotic properties.		Caspase , HIV Protease
T6255	Bromosporine		Epigenetic Reader Domain , CDK
	Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively.		Epigenetic Reader Domain , CDK
T11281L	FGI-106 tetrahydrochloride		Virus Protease , HCV Protease , Influenza Virus , HIV Protease

T16154	MS417	GTPL7512	Epigenetic Reader Domain , HIV Protease
	MS417 (GTPL7512) is an inhibitor of BET-specific BRD4(BRD4-BD1 and BRD4-BD2 with IC50s of 30, 46 nM and Kds of 36.1, 25.4 nM, respectively), with weak selectivity at CBP BRD with IC50 of 32.7 μM.		Epigenetic Reader Domain , HIV Protease
T6214	Emtricitabine	FTC,Emtriva,BW1592	HIV Protease , Reverse Transcriptase
	Emtricitabine (FTC) (FTC), a nucleoside reverse transcriptase inhibitor, exhibits inhibition activity against human immunodeficiency virus (HIV) and hepatitis B virus.		HIV Protease , Reverse Transcriptase

Compounds

Target: Others, HIV Protease

Sodium copper chlorophyllin B

T12953

Synonym:

Target: Influenza Virus, HIV Protease

3-Deazaadenosine hydrochloride

T10111

Synonym:

Target: Others, HIV Protease

Reverse transcriptase-IN-1

Target: gp120/CD4, HIV Protease

Synonym: Elpida,VM-1500

Target: HIV Protease

Sulfadoxine

T0836

Synonym: Sulphadoxine

Target: DHFR, HIV Protease, Antibiotic, Parasite, Autophagy

Probenecid

T0457

Synonym: Benemid

Target: HIV Protease, Antibacterial, TRP/TRPV Channel

Obefazimod

T8311

Synonym: ABX-464,ABX464

Target: HIV Protease, Reverse Transcriptase

IMB-301

T9212

Synonym:

Target: Others, HIV Protease

ZL0580

T13974

Synonym:

Target: Epigenetic Reader Domain, HIV Protease

9-Aminoacridine

T0289

Synonym: Aminacrine

Target: Others, HIV Protease, Antibacterial

Synonym: 5-Methyl-2-Pentylphenol

Target: Others, HIV Protease

Gardiquimod

T15371

Synonym:

Target: TLR, HIV Protease

BRD-6929

T10603

Synonym:

Target: HIV Protease, HDAC

3'-Azido-3'-deoxy-5-methylcytidine

T10133

Synonym:

Target: Antiviral, HIV Protease

Hck-IN-1

T11538

Synonym:

Target: HIV Protease, Src, Hck

Dimercaprol

T0781

Synonym: Dicaptol,Dithiopropanol

Target: Others, HIV Protease

Vesatolimod

T6846

Synonym: GS-9620

Target: Apoptosis, HCV Protease, HBV, TLR, HIV Protease

Fostemsavir Tris

T10570

Synonym: BMS-663068 Tris

Target: Apoptosis, IAP, HIV Protease

Fosamprenavir Calcium Salt

T8238

Synonym: Diallyl Trisulfide,GW433908G

Target: HIV Protease

Miltefosine

T0033

Synonym: HePC,Hexadecyl phosphocholine

Target: Akt, HIV Protease, PKC

Raltegravir

T2239L

Synonym: MK-0518

Target: HIV Protease, Integrase

Inosine pranobex

T3614

Synonym: Groprinosin,Isoprinosine,Immunovir,Delimmun

Target: IL Receptor, HIV Protease

Lenacapavir

T11465

Synonym: GS-6207

Target: Others, HIV Protease

Salicylanilide

T0753

Synonym: WR10019,2-Hydroxybenzanilide

Target: HIV Protease, Reverse Transcriptase

Target: SARS-CoV, HIV Protease

Hydroxyurea

T0676

Synonym: Hydroxycarbamide,nsc32065,nci-c04831

Target: Apoptosis, HIV Protease, DNA/RNA Synthesis, Autophagy

Ditiocarb sodium

T5965

Synonym: Sodium diethyldithiocarbamate

Target: HIV Protease

Des(benzylpyridyl) Atazanavi

Target: Epigenetic Reader Domain, HIV Protease

Q-VD-OPH

T0282

Synonym: Quinoline-Val-Asp-Difluorophenoxymethylketone

Target: Caspase, HIV Protease

Bromosporine

T6255

Synonym:

Target: Epigenetic Reader Domain, CDK

FGI-106 tetrahydrochloride

T11281L

Synonym:

Target: Virus Protease, HCV Protease, Influenza Virus, HIV Protease

MS417

T16154

Synonym: GTPL7512

Target: Epigenetic Reader Domain, HIV Protease

Emtricitabine

T6214

Synonym: FTC,Emtriva,BW1592

Target: HIV Protease, Reverse Transcriptase

カタログ番号	製品名	別名	ターゲット
T6377	Aloperine		Apoptosis , Virus Protease , HIV Protease , Antibiotic , Autophagy
	Aloperine exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.
TN2283	Tripterifordin		HIV Protease
	Tripterifordin shows anti-HIV replication activity in H9 lymphocyte cells with an EC50 of 1 microgram/ml.		HIV Protease
T2942	Psoralen	Ficusin,Furocoumarin,psoralene	Apoptosis , Influenza Virus , HIV Protease , DNA/RNA Synthesis
	Psoralen (Ficusin) is a furocoumarin that intercalates with DNA, inhibiting DNA synthesis and cell division.
TQ0217	Gomisin G		P450 , HIV Protease
	Gomisin G is a natural compound and exhibits potent anti-HIV activity (EC50: 0.006 μg/mL; therapeutic index: 300). It is a good substrate of CYP2C9.		P450 , HIV Protease
TN1103	Diphyllin		ATPase , Proton pump , Influenza Virus , HIV Protease
	Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling.		ATPase , Proton pump , Influenza Virus , HIV Protease
T0474	Erythromycin ethylsuccinate	EES	ribosome , HIV Protease , Antibacterial , Antibiotic , Autophagy
	Erythromycin ethylsuccinate (EES) is a macrolide antibiotic, produced by Streptomyces erythreus.
Fr16741	Oxindole	Indolin-2-one	Others , HIV Protease
	Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.Oxindole structure has been used in receptor tyrosine kinases ...		Others , HIV Protease
T3822	Bellidifolin	Bellidifoline,Bellidifolium	Others , HIV Protease
	Bellidifolin (Bellidifoline) has anti-oxidation, hepatoprotective, anti-inflammatory and antitumor actions, it may contribute to the protective effects associated with nerve injury initiated by hypoxia by mechanisms rela...		Others , HIV Protease
T2865	Oleanolic Acid	Oleanic acid,Caryophyllin	HIV Protease , Endogenous Metabolite , Antibiotic , Autophagy
	Oleanolic Acid (Caryophyllin) is a natural compound with anti-tumor activities, which are widely distributed in plants.
T0966	Sennoside A	NSC 112929	MAO , HIV Protease
	Sennoside A (NSC-112929), a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine.		MAO , HIV Protease
T6841	Fumagillin	NSC9168,Amebacilin	Others , HIV Protease , Antibiotic , Parasite
	Fumagillin (Amebacilin) is a selective and potent irreversible inhibitor of Methionine aminopeptidase 2 (MetAP2), used as an antibiotic to treat microsporidiosis.		Others , HIV Protease , Antibiotic , Parasite
T1131	Ivermectin	MK-933	Mitophagy , GluCls , P2X Receptor , SARS-CoV , HIV Protease , Antibiotic , Parasite , Autophagy , HSV
	Ivermectin (MK-933) is a glutamate-gated chloride channel (GluCls) activator, with antiparasitic activity.
T8689	Chloroquine	CQ	SARS-CoV , TLR , HIV Protease , Antibiotic , Parasite , Autophagy
	Chloroquine is a Toll-like receptor inhibitor that inhibits autophagy. Chloroquine has anti-malarial and anti-inflammatory activity and is widely used in the treatment of malaria and rheumatoid arthritis. Chloroquine als...
T8116	Azulene	Bicyclo[5.3.0]Decapentaene	Others , HIV Protease
	Azulene (Bicyclo[5.3.0]Decapentaene) is a natural product.		Others , HIV Protease
T2177	Kaempferol	Kempferol,Robigenin	Apoptosis , Estrogen Receptor/ERR , Mitophagy , Estrogen/progestogen Receptor , HIV Protease , Endogenous Metabolite , Parasite , Autophagy
	Kaempferol (Robigenin) is a natural flavonoid and an inverse agonist of ERRα and ERRγ. Kaempferol has a wide range of antitumor, anti-inflammatory, antioxidant, antibacterial and antiviral activities.
T2S0731	Trilobatin	P-Phlorizin	Amylase
	Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentially inhibits the lipopolysaccharide (LPS)-induced inflammatory respon...		Amylase
T0492	Dimethyl fumarate	DMF	Reactive Oxygen Species , HIV Protease , Nrf2 , Endogenous Metabolite , Autophagy
	Dimethyl fumarate (DMF), a fumarate derivative, is used as antiinflammatory and immunomodulatory agent.
T4962	Zingibroside R1	Ginsenoside Z-R1	HIV Protease
	Zingibroside R1 (Ginsenoside Z-R1) has anti-HIV-1 activity.		HIV Protease
T2728	Limonin	Dictamnolactone,Limonoic acid 3,19:16,17 dilactone,Obaculactone,Citrolimonin	Apoptosis , HIV Protease , Endogenous Metabolite
	Limonin (Citrolimonin) is a triterpenoid enriched in citrus fruits, which has antivirus and antitumor ability.		Apoptosis , HIV Protease , Endogenous Metabolite
T2789	Scutellarin	Breviscapin,Breviscapinun,Breviscapine,Scutellarein-7-glucuronide	Akt , HIV Protease , STAT
	Scutellarin (Scutellarein-7-glucuronide), an active flavone isolated from Scutellaria baicalensis, can inhibit RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts, and down-regulate the STAT3/Girdin/Akt signal...		Akt , HIV Protease , STAT
T1284	Megestrol acetate	SC10363,BDH1298	Glucocorticoid Receptor , Estrogen/progestogen Receptor , Progesterone Receptor , HIV Protease , Autophagy
	Megestrol acetate (BDH1298) is a progestogen with actions and uses similar to those of the progestogens in general. Megestrol acetate also has anti-androgenic properties. It is given by mouth in the palliative treatment ...
T7991	2-Hydroxycinnamic acid		Others , SARS-CoV , HIV Protease
	2-Hydroxycinnamic acid is a natural product isolated from Angraecum fragrans, has photooxidant activity.		Others , SARS-CoV , HIV Protease
T5429	Theaflavin 3,3'-digallate	8-Gingerol,TFDG	Virus Protease , Antioxidant , HIV Protease , HSV
	Theaflavin 3,3'-digallate (8-Gingerol) , a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancer chemopreventive actions, it reduces tumor angiogenesis by downregul...		Virus Protease , Antioxidant , HIV Protease , HSV
T3122	Fangchinoline	Tetrandrine B,(+)-Limacine,Hanfangichin B,(+)-Fangchinoline	Apoptosis , FAK , HIV Protease , Autophagy
	Fangchinoline (Tetrandrine B) is extracted from Stephania tetrandra S. Moore.		Apoptosis , FAK , HIV Protease , Autophagy
T16791	Rottlerin	Mallotoxin,NSC 56346,NSC 94525	CaMK , Apoptosis , Others , HIV Protease , PKA , PKC , Autophagy
	Rottlerin (NSC-56346) is a natural product purified from Mallotus Philippinensis and is a specific PKC inhibitor (IC50: PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKCε,η,ζ of 80-100 μM). Rottlerin causes apoptosis via caspase...
T3730	Methyl gallate	NSC 363001,Gallicin,Gallic acid methyl ester,Gallincin	Reactive Oxygen Species , HIV Protease , Reverse Transcriptase , Antibacterial
	Methyl gallate (Gallincin) is a reverse transcriptase inhibitor with antioxidant, anti-HIV-1 and HIV-1 enzyme inhibition activities.
T2775	Baicalin	Baicalein 7-O-β-D-glucuronide	NF-κB , HIV Protease , GABA Receptor , Autophagy
	Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIV properties.		NF-κB , HIV Protease , GABA Receptor , Autophagy
T1020	Doxorubicin hydrochloride	Adriamycin,Doxorubicin (Adriamycin) HCl,Hydroxydaunorubicin hydrochloride,NSC 123127	Apoptosis , Mitophagy , HBV , HIV Protease , Topoisomerase , Antibacterial , Antibiotic , AMPK , Autophagy
	Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM). Doxorubicin hydrochloride exhibits cytotoxicity and antitum...
T2830	Betulinic acid	ALS-357,Lupatic acid,Betulic acid	Apoptosis , Mitophagy , NF-κB , HIV Protease , Topoisomerase , Endogenous Metabolite , Aminopeptidase , Autophagy
	Betulinic acid (ALS-357) is a pentacyclic lupane-type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) which has antiretroviral, antimalarial, and anti-inflammatory propert...
T5782	Bevirimat	YK FH312,MPC-4326,PA-457	HIV Protease
	Bevirimat (PA-457) is a first-in-class inhibitor of HIV-1 maturation, blocking the cleavage of the Gag capsid (CA) precursor, CA-SPI, to mature CA protein during virion maturation.		HIV Protease
T0194	Chloroquine phosphate	Chloroquine diphosphate,Aralen phosphate,Chingamin phosphate	SARS-CoV , TLR , HIV Protease , Antibiotic , Parasite , Autophagy
	Chloroquine phosphate (Aralen phosphate) is an aminoquinoline antimalarial and also is widely used as an autophagy inhibitor. Chloroquine also is an inhibitor of toll-like receptors (TLRs).
T6S2391	L-Chicoric Acid	(-)-Chicoric acid,trans-Caffeoyltartaric acid,Chicoric acid,dicaffeoyltartaric acid	Others , HIV Protease
	L-Chicoric Acid (trans-Caffeoyltartaric acid) has been shown to inhibit hyaluronidase and HIV-1 integrase, and to possess phagoeytosis stimulatory activity in vitro and in vivo and antiviral acitivy. L-Chicoric acid may ...		Others , HIV Protease
T0710	L-Cycloserine	Levcycloserine,Levcicloserina,(-)-Cycloserine,(S)-Cycloserine,Levcycloserinum,(S)-4-Amino-3-isoxazolidone	HIV Protease , GABA Receptor
	L-Cycloserine ((-)-Cycloserine) irreversibly inhibits GABA pyridoxal 5′-phosphate-dependent aminotransferase in E. coli, as well in the brains of various animals, results in increased levels of gamma-aminobutyric acid (G...		HIV Protease , GABA Receptor
T3772	Maslinic acid	2α-Hydroxyoleanoic Acid,2α-Hydroxyoleanolic acid,Crategolic acid	NF-κB , HIV Protease , DNA/RNA Synthesis , Antibacterial
	Maslinic acid (Crategolic acid) is a DNA polymerase B inhibitor.		NF-κB , HIV Protease , DNA/RNA Synthesis , Antibacterial
T0070	Pentoxifylline	Oxpentifylline,PTX,BL-191	HIV Protease , PDE , Adenosine Receptor , Autophagy
	Pentoxifylline (PTX) modulates immunologic activity by stimulating cytokine production. Pentoxifylline is a methylxanthine derivative that inhibits phosphodiesterase and affects blood rheology. It also inhibits platelet ...		HIV Protease , PDE , Adenosine Receptor , Autophagy
T3321	Oleanonic acid	3-Oxooleanolic acid,3-Oxoolean-12-en-28-oic Acid,Oleanonic Acid,3-Ketooleanolic Acid	HIV Protease
	Oleanonic acid (3-Ketooleanolic Acid) is relatively non-toxic, hepatoprotective, and exhibits antitumor and andantiviral properties.		HIV Protease
T22468	1-Deoxymannojirimycin hydrochloride		Others , Influenza Virus , HIV Protease
	α-mannosidase I inhibitor		Others , Influenza Virus , HIV Protease
T1125	Shikonin	NSC 252844,Isoarnebin 4,(+)-Shikonin,Alkanna Red,C.I. 75535,Anchusa acid	TNF , NF-κB , Chloride channel , HIV Protease , PKM
	Shikonin (Anchusa acid) is a natural product, a TMEM16A chloride channel inhibitor (IC50=6.5 μM) and selective PKM2 inhibitor. Shikonin exhibits antitumor, anti-inflammatory and wound healing activities.		TNF , NF-κB , Chloride channel , HIV Protease , PKM
T7064	Valproic Acid	Sodium valproate,2-Propylpentanoic Acid,VPA,Depakine,2-Propylvaleric Acid	Mitophagy , Gamma-secretase , HIV Protease , GABA Receptor , Sodium Channel , HDAC , Autophagy
	Valproic Acid (2-Propylpentanoic Acid) is an HDAC inhibitor that inhibits HDAC1 activity, induces HDAC2 degradation, and is orally active. Valproic Acid can be used in epilepsy and bipolar disorder research.
T1456	Doxorubicin	Hydroxydaunorubicin,Adriamycin	Topoisomerase , AMPK
			Topoisomerase , AMPK
T0200	α-Lipoic Acid	Thioctic acid,DL-α-Lipoic acid,(±)-α-Lipoic acid	Apoptosis , NF-κB , HIV Protease , Mitochondrial Metabolism , Endogenous Metabolite
	α-Lipoic Acid (DL-α-Lipoic acid) an octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme ...
T5783	Rosamultin		Antioxidant , HIV Protease
	Rosamultin has antioxidant, antiinflammatory/antinociceptive properties,and has anti-human immunodeficiency virus (HIV) activity.		Antioxidant , HIV Protease
T4537	Cholic acid sodium	SodiumCholate	HIV Protease , Endogenous Metabolite
	Cholic acid sodium (SodiumCholate) exhibits a strong spermicidal and antiviral [anti-human immunodeficiency virus (HIV)-1] activity.		HIV Protease , Endogenous Metabolite
TL0006	Cichoric Acid	Dicaffeoyltartaric acid,Chicoric Acid	Reactive Oxygen Species , HIV Protease
	Cichoric Acid (Dicaffeoyltartaric acid) is a potent inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tissues. It also a class of cannabinomimetics with CB2 receptor-dependent and ...		Reactive Oxygen Species , HIV Protease
TN2231	Soyasaponin II		Influenza Virus , HIV Protease , HSV
	Soyasaponin II has antiviral effects, it can inhibit the replication of human cytomegalovirus, influenza virus, and human immunodeficiency virus type 1.		Influenza Virus , HIV Protease , HSV
TN4109	Ganolucidic acid A		HIV Protease
	Ganolucidic acid A exhibits cytotoxicity, has inhibitory activities against human HeLa cervical cancer cell lines. It shows significant anti-human immunodeficiency virus (anti-HIV)-1 protease activity with IC50 values of...		HIV Protease
TMA1012	Ganoderiol F		Androgen Receptor , HIV Protease , Autophagy
	Ganoderiol F has anti-inflammatory, cytotoxic and anti-HIV activity, it inhibits activity of topoisomerases in vitro, and it inhibits human immunodeficiency virus-1 protease with IC(50) values of 20-40 microM. It induced...		Androgen Receptor , HIV Protease , Autophagy

天然物製品

Aloperine

T6377

Synonym:

Target: Apoptosis, Virus Protease, HIV Protease, Antibiotic, Autophagy

Synonym: Ficusin,Furocoumarin,psoralene

Target: Apoptosis, Influenza Virus, HIV Protease, DNA/RNA Synthesis

Gomisin G

TQ0217

Synonym:

Target: P450, HIV Protease

Diphyllin

TN1103

Synonym:

Target: ATPase, Proton pump, Influenza Virus, HIV Protease

Erythromycin ethylsuccinate

T0474

Synonym: EES

Target: ribosome, HIV Protease, Antibacterial, Antibiotic, Autophagy

Oxindole

Fr16741

Synonym: Indolin-2-one

Target: Others, HIV Protease

Bellidifolin

T3822

Synonym: Bellidifoline,Bellidifolium

Target: Others, HIV Protease

Oleanolic Acid

T2865

Synonym: Oleanic acid,Caryophyllin

Target: HIV Protease, Endogenous Metabolite, Antibiotic, Autophagy

Sennoside A

T0966

Synonym: NSC 112929

Target: MAO, HIV Protease

Fumagillin

T6841

Synonym: NSC9168,Amebacilin

Target: Others, HIV Protease, Antibiotic, Parasite

Ivermectin

T1131

Synonym: MK-933

Target: Mitophagy, GluCls, P2X Receptor, SARS-CoV, HIV Protease, Antibiotic, Parasite, Autophagy, HSV

Chloroquine

T8689

Synonym: CQ

Target: SARS-CoV, TLR, HIV Protease, Antibiotic, Parasite, Autophagy

Azulene

T8116

Synonym: Bicyclo[5.3.0]Decapentaene

Target: Others, HIV Protease

Kaempferol

T2177

Synonym: Kempferol,Robigenin

Target: Apoptosis, Estrogen Receptor/ERR, Mitophagy, Estrogen/progestogen Receptor, HIV Protease, Endogenous Metabolite, Parasite, Autophagy

Target: Reactive Oxygen Species, HIV Protease, Nrf2, Endogenous Metabolite, Autophagy

Zingibroside R1

T4962

Synonym: Ginsenoside Z-R1

Target: HIV Protease

Limonin

T2728

Synonym: Dictamnolactone,Limonoic acid 3,19:16,17 dilactone,Obaculactone,Citrolimonin

Target: Apoptosis, HIV Protease, Endogenous Metabolite

Scutellarin

T2789

Synonym: Breviscapin,Breviscapinun,Breviscapine,Scutellarein-7-glucuronide

Target: Akt, HIV Protease, STAT

Megestrol acetate

T1284

Synonym: SC10363,BDH1298

Target: Glucocorticoid Receptor, Estrogen/progestogen Receptor, Progesterone Receptor, HIV Protease, Autophagy

2-Hydroxycinnamic acid

T7991

Synonym:

Target: Others, SARS-CoV, HIV Protease

Theaflavin 3,3'-digallate

T5429

Synonym: 8-Gingerol,TFDG

Target: Virus Protease, Antioxidant, HIV Protease, HSV

Fangchinoline

T3122

Synonym: Tetrandrine B,(+)-Limacine,Hanfangichin B,(+)-Fangchinoline

Target: Apoptosis, FAK, HIV Protease, Autophagy

Rottlerin

T16791

Synonym: Mallotoxin,NSC 56346,NSC 94525

Target: CaMK, Apoptosis, Others, HIV Protease, PKA, PKC, Autophagy

Methyl gallate

T3730

Synonym: NSC 363001,Gallicin,Gallic acid methyl ester,Gallincin

Target: Reactive Oxygen Species, HIV Protease, Reverse Transcriptase, Antibacterial

Baicalin

T2775

Synonym: Baicalein 7-O-β-D-glucuronide

Target: NF-κB, HIV Protease, GABA Receptor, Autophagy

Doxorubicin hydrochloride

T1020

Synonym: Adriamycin,Doxorubicin (Adriamycin) HCl,Hydroxydaunorubicin hydrochloride,NSC 123127

Target: Apoptosis, Mitophagy, HBV, HIV Protease, Topoisomerase, Antibacterial, Antibiotic, AMPK, Autophagy

Betulinic acid

T2830

Synonym: ALS-357,Lupatic acid,Betulic acid

Target: Apoptosis, Mitophagy, NF-κB, HIV Protease, Topoisomerase, Endogenous Metabolite, Aminopeptidase, Autophagy

Bevirimat

T5782

Synonym: YK FH312,MPC-4326,PA-457

Target: HIV Protease

Chloroquine phosphate

T0194

Synonym: Chloroquine diphosphate,Aralen phosphate,Chingamin phosphate

Target: SARS-CoV, TLR, HIV Protease, Antibiotic, Parasite, Autophagy

L-Chicoric Acid

T6S2391

Synonym: (-)-Chicoric acid,trans-Caffeoyltartaric acid,Chicoric acid,dicaffeoyltartaric acid

Target: Others, HIV Protease

L-Cycloserine

T0710

Synonym: Levcycloserine,Levcicloserina,(-)-Cycloserine,(S)-Cycloserine,Levcycloserinum,(S)-4-Amino-3-isoxazolidone

Target: HIV Protease, GABA Receptor

Maslinic acid

T3772

Synonym: 2α-Hydroxyoleanoic Acid,2α-Hydroxyoleanolic acid,Crategolic acid

Target: NF-κB, HIV Protease, DNA/RNA Synthesis, Antibacterial

Pentoxifylline

T0070

Synonym: Oxpentifylline,PTX,BL-191

Target: HIV Protease, PDE, Adenosine Receptor, Autophagy

Oleanonic acid

T3321

Synonym: 3-Oxooleanolic acid,3-Oxoolean-12-en-28-oic Acid,Oleanonic Acid,3-Ketooleanolic Acid

Target: HIV Protease

1-Deoxymannojirimycin hydrochloride

T22468

Synonym:

Target: Others, Influenza Virus, HIV Protease

Shikonin

T1125

Synonym: NSC 252844,Isoarnebin 4,(+)-Shikonin,Alkanna Red,C.I. 75535,Anchusa acid

Target: TNF, NF-κB, Chloride channel, HIV Protease, PKM

Valproic Acid

T7064

Synonym: Sodium valproate,2-Propylpentanoic Acid,VPA,Depakine,2-Propylvaleric Acid

Target: Mitophagy, Gamma-secretase, HIV Protease, GABA Receptor, Sodium Channel, HDAC, Autophagy

Doxorubicin

T1456

Synonym: Hydroxydaunorubicin,Adriamycin

Target: Topoisomerase, AMPK

α-Lipoic Acid

T0200

Synonym: Thioctic acid,DL-α-Lipoic acid,(±)-α-Lipoic acid

Target: Apoptosis, NF-κB, HIV Protease, Mitochondrial Metabolism, Endogenous Metabolite

Rosamultin

T5783

Synonym:

Target: Antioxidant, HIV Protease

Cholic acid sodium

T4537

Synonym: SodiumCholate

Target: HIV Protease, Endogenous Metabolite

Cichoric Acid

TL0006

Synonym: Dicaffeoyltartaric acid,Chicoric Acid

Target: Reactive Oxygen Species, HIV Protease

Soyasaponin II

TN2231

Synonym:

Target: Influenza Virus, HIV Protease, HSV

Target: Androgen Receptor, HIV Protease, Autophagy

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-04989	Galectin-9 Protein, Human, Recombinant (hFc)	Human	HEK293
	LGALS9 (Galectin 9) is a Protein Coding gene. 6 alternatively spliced human isoforms have been reported. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix ...
TMPY-00586	CLEC-2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	CLEC1B, also known as CLEC2, is a C-type lectin-like receptor expressed in myeloid cells and NK cells. Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 and NKG2D, ...
TMPY-01827	CD30/TNFRSF8 Protein, Human, Recombinant (His)	Human	HEK293
	CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of...
TMPY-02257	CCL14 Protein, Human, Recombinant (His)	Human	E. coli
	CCL14 has an important biological role in other mammals by evolving under positive selection that has been lost in Ochotonidae (subgenera Pika and Lagotona). CC chemokine ligand 14, CCL14, is a human CC chemokine that is...
TMPY-02468	CCL14 Protein, Human, Recombinant (aa 28-93, His)	Human	E. coli
	CCL14 has an important biological role in other mammals by evolving under positive selection that has been lost in Ochotonidae (subgenera Pika and Lagotona). CC chemokine ligand 14, CCL14, is a human CC chemokine that is...
TMPY-02357	CLEC-2 Protein, Human, Recombinant (His)	Human	HEK293
	CLEC1B, also known as CLEC2, is a C-type lectin-like receptor expressed in myeloid cells and NK cells. Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 and NKG2D, ...
TMPH-01555	IFITM1 Protein, Human, Recombinant (GST)	Human	E. coli
	IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against ...
TMPY-06032	CD30/TNFRSF8 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of...
TMPY-05471	CD30/TNFRSF8 Protein, Human, Recombinant (hFc)	Human	HEK293
	CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of...
TMPY-05118	CD30/TNFRSF8 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of...
TMPY-05443	CD30/TNFRSF8 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of...
TMPY-06430	CD30/TNFRSF8 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of...
TMPY-05737	CD30/TNFRSF8 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of...
TMPY-06282	CD30/TNFRSF8 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293
	CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of...
TMPY-03963	CALCB Protein, Human, Recombinant (mFc)	Human	HEK293
	CALCB, also known as CGPR and calcitonin 2, belongs to the calcitonin family. CALCB is a calcitonin (CT) peptide which may play a role in the mediation of human inflammatory diseases. It is highly expressed in the skin, ...
TMPY-01383	PRMT6 Protein, Human, Recombinant (His & Flag)	Human	HEK293
	Protein arginine N-methyltransferase 6, also known as Histone-arginine N-methyltransferase PRMT6, PRMT6, and HRMT1L6, is a member of the protein arginine N-methyltransferase family and PRMT6 subfamily. PRMT6 is highly ex...
TMPH-01248	ADAR Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translatio...
TMPH-01249	ADAR Protein, Human, Recombinant (GST)	Human	E. coli
	Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translatio...
TMPK-01523	Chimeric HLA-A02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human*&Mouse, MHC (His & Avi)	Human & Mouse	HEK293
	The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, en...
TMPK-01522	Chimeric HLA-A02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human*&Mouse, MHC (His & Avi)	Human & Mouse	HEK293
	The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, en...
TMPK-01535	Chimeric HLA-A02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human*&Mouse, MHC (His & Avi)	Human & Mouse	HEK293
	The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel...
TMPK-01534	Chimeric HLA-A02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human*&Mouse, MHC (His & Avi)	Human & Mouse	HEK293
	The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel...